Analog peripheral perfusion monitor using NIR PPG and lock-in without microcontrollers

Authors

DOI:

https://doi.org/10.70208/3007.8245.v6.n1.373

Keywords:

photoplethysmography, perfusion index, synchronous demodulation, lock-in, biomedical instrumentation

Abstract

Peripheral perfusion is a relevant indicator of vasomotor tone and hemodynamic status, particularly in triage, hypothermia, and early shock. Conventional photoplethysmography (PPG) can be degraded by ambient light and motion artifacts, compromising derived metrics such as the perfusion index (PI). This paper presents the design of a fully analog peripheral perfusion monitor powered by DC rails (+12 V and +5 V) using near-infrared PPG (940 nm) with optical modulation (3–10 kHz) and lock-in synchronous demodulation implemented via analog switching and baseband filtering. PI is defined as AC/DC×100% of the plethysmographic waveform, and its estimation is proposed using the AC envelope (pulsatile component) and the DC level (non-pulsatile component), providing 0–5 V analog outputs and a TTL pulse output for heart-rate counting. The work details functional blocks, initial component values, transimpedance stability considerations, and safety-oriented guidelines informed by IEC 60601-1. A reproducible validation protocol (occlusion, cold exposure, and post-exercise) is also proposed to quantify PI trends and compare them against a commercial pulse oximeter as an operational reference.

References

Cannesson, M., Attof, Y., Rosamel, P., Desebbe, O., Joseph, P., Metton, O., & Bastien, O. (2009). Recent advances in pulse oximetry. Anesthesiology Research and Practice, 2009, Article 364021.

Coutrot, M., Bouzat, P., & Buisson, M. (2021). Perfusion index: Physical principles, physiological meanings and clinical implications. Trends in Anaesthesia and Critical Care.

Fine, J., Branan, K. L., Rodriguez, A. J., Boonya-ananta, T., Ramella-Roman, J. C., McShane, M. J., & Coté, G. L. (2021). Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring. Biosensors, 11(4), 126.

Horowitz, P., & Hill, W. (2015). The art of electronics (3rd ed.). Cambridge University Press.

International Electrotechnical Commission. (2012). IEC 60601-1: Medical electrical equipment—Part 1: General requirements for basic safety and essential performance (Consolidated version).

Park, J., Kim, J., Kim, S., & Park, C. (2022). Photoplethysmogram analysis and applications: An integrative review. Sensors, 22(6), 2429.

Sedra, A. S., & Smith, K. C. (2014). Microelectronic circuits (7th ed.). Oxford University Press.

U.S. Patent No. 5,954,644. (1999). Method for ambient light subtraction in a photoplethysmographic measurement system. U.S. Patent and Trademark Office.

Published

2026-03-31

How to Cite

Luigi Dalporto , B. A. (2026). Analog peripheral perfusion monitor using NIR PPG and lock-in without microcontrollers. Horizonte Academico, 6(1), 899–928. https://doi.org/10.70208/3007.8245.v6.n1.373

Issue

Section

Artículos