Toxic compounds in vaping liquids and their effect on lung function: narrative Review
DOI:
https://doi.org/10.70208/3007.8245.v6.n1.419Keywords:
electronic cigarettes, vaping, e-liquids, toxic compounds, lung functionAbstract
In recent years, the use of electronic cigarettes has increased considerably, raising concerns about their potential effects on respiratory health. Vaping products contain many chemical components and can be altered when heated or aerosolized into harmful compounds. The objective of this work is to analyze the current evidence on toxic compounds in vaping liquids and their effect on lung function. The methodology was a narrative literature review was conducted, including studies accessed through electronic databases such as PubMed, Scopus, Web of Science, and Google Scholar, in English and Spanish, published between 2021 and 2026. Terms used included "electronic cigarettes," "vaping," "e-liquids," "toxic compounds," "lung function," "pulmonary effects," and "respiratory health." The results of this research demonstrate a reduction in lung capacity and respiratory tissue immune response in regular users and experimental models. Therefore, while they may be considered a more benign substitute for standard inhalation, e-cigarettes also contain toxins that can affect lung capacity. Longitudinal studies will be needed to gain a better understanding of their long-term impact and to strengthen health regulations.
References
American Lung Association. (2026). Health risks of e-cigarettes and vaping.
Calderon, C. P. G., Vargas, Y. A. C., & Forero-Forero, J. C. (2022). Lesión pulmonar asociada al uso de cigarrillos electrónicos o productos de vapeo (EVALI): a propósito de un caso relacionado a neumonía eosinofílica aguda. Revista Colombiana de Neumología, 34(1), 46-51.
Cebrián-Cortés, A., Sánchez-Gaona, I., Pérez-Villares, J. M., & Cárdenas-Cruz, A. (2025). Lesión pulmonar asociada al consumo de cigarrillos electrónicos o vapeo: una revisión narrativa. Medicina Intensiva, 502345.
Fiallos, S. L. F. (2024). Impacto de vapeadores o cigarrillos electrónicos en la salud: una revisión de la evidencia científica. Latam: revista latinoamericana de Ciencias Sociales y Humanidades, 5(5), 23.
Findlay-Greene, F., Donnellan, S., & Vass, S. (2025). Analysing the acute toxicity of e-cigarette liquids and their vapour on human lung epithelial cells. Toxicology Reports.
Ghosh, A., et al. (2024). Effects of vaping on respiratory health: A systematic review.
Gómez-Bonilla, M. A., Lopez-Díaz, I., Lozano-Marulanda, S., & Asencio-Santofimio, H. A. (2023). El vapeo como hábito de los adolescentes y jóvenes en Colombia: Una revisión de la literatura. Salutem Scientia Spiritus, 9(4), 66-70.
Hopkins, Johns. (2025). New analysis underscores health risks of e-cigarettes.
Jaimes, M. L. P., Servin, H. L. O., Argueta, I. G., Sánchez, M. H., Beiza, I. R. C., & García, J. J. (2026). Vapear o No Vapear, en el 2026 ¡Esa es la Decisión! Ibero Ciencias-Revista Científica y Académica-ISSN 3072-7197, 5(1), 1190-1199.
López, A. V., Garnica, A. E. G., & Robelo, M. D. C. R. (2025). Estudio del efecto de vapeadores y cigarros electrónicos en la salud de la población adolescente. JÓVENES EN LA CIENCIA, 37, 1-15.
López, S. T. (2022). Uso de vapeadores como factor de riesgo de injuria pulmonar aguda. Revista CES Salud Pública y Epidemiología, 1(2), 121-137.
Martínez-Larenas, M. V., Montañez-Aguirre, Á. A., González-Valdelamar, C. A., Fraga-Duarte, M., Cossío-Rodea, G., & Vera-López, J. C. (2022). Efectos fisiopatológicos del cigarro electrónico: un problema de salud pública. Neumología y cirugía de tórax, 81(2), 121-130.
Montana C. A., Salas H. A. A., Bonilla D. M. A, Lomelí O. J. C. y Ibarra P. O. J (2022) RIESGOS DEL USO DE VAPEADOR EN ESTUDIANTES. Revista de divulgación científica, Universidad de Xochicalco. 10(25) 28-33.
Rao, R., et al. (2025). Investigating the effects of vaping on lung structure-function. American Journal of Respiratory and Critical Care Medicine.
Tehrani, M. W., et al. (2021). Characterizing chemicals in e-cigarette liquids and aerosols. Chemical Research in Toxicology.
Tigse, A. G. E., & Castillo, Y. M. C. (2024). Alteraciones respiratorias y sistémicas asociadas al uso de cigarrillos electrónicos. Revista UNIANDES de Ciencias de la Salud, 7(3), 305-326.













